The most common types of clinical questions:
Therapy -- Investigating how well an intervention works to improve outcomes that matter to patients, such as reducing symptoms, improving quality of life, or preventing complications.
- In _____, what is the effect of _____ on _____ compared with _____?
In adults with chronic low back pain, does yoga therapy compared to standard physical therapy reduce pain and improve mobility?
Diagnosis -- Assessing how accurately a test identifies who has/doesn't have a particular condition.
- For _____, does the use of _____ reduce the future risk of _____ compared with _____?
In children with suspected strep throat, how accurate is the rapid antigen detection test compared to throat culture?
Etiology-- Exploring the risks or negative effects that exposures or treatments might have on patient health.
- Are _____ who have _____ at risk of/for _____ compared with _____ with/without _____?
In patients using NSAIDs long-term, how does NSAID use compared to non-use affect the risk of gastrointestinal bleeding?
Prognosis -- Predicting what will likely happen to a patient over time.
- Does _____ influence _____ in patients who have _____?
In older adults hospitalized with heart failure, does participation in a cardiac rehabilitation program compared to no rehabilitation reduce the risk of hospital readmission within 6 months?
Prevention -- Evaluating strategies to stop a disease or condition before it starts.
- For _____, does the use of _____ reduce the future risk of _____ compared with _____?
In adults over the age of 50 at risk of cardiovascular disease, does daily aspirin use compared to no aspirin use reduce the incidence of heart attack over five years?